Wright Lab
David Geffen School of Medicine at UCLA

Recent Publications: 

 

  • Wright, E.M. (2021)  SGLT2 Inhibitors: Physiology and Pharmacology. Kidney 360 2(11): 1-11. ISSN(E) 2641-7650, DOI 0.34067/KID.0002772021.
     

  • Ernest M Wright, Donald D F Loo, Active Glucose Transport 2020 and Beyond, Function, Volume 2, Issue 1, 2021, zqaa047, https://doi.org/10.1093/function/zqaa047

  • Donald D F Loo, Ernest M Wright, Regulation of Neutral Amino Acid Transport by the SARS-CoV-2 Receptor ACE2, Function, 2021; zqab048, https://doi.org/10.1093/function/zqab048

  • M Pilar Lostao, Donald D Loo, Olle Hernell, Gunnar Meeuwisse, Martin G Martin, Ernest M Wright, The Molecular Basis of Glucose Galactose Malabsorption in a Large Swedish Pedigree, Function, Volume 2, Issue 5, 2021, zqab040, https://doi.org/10.1093/function/zqab040

  • Loo D.D.F., Wright E.M. (2021) Sugar Transport Across Epithelia. In: Hamilton K.L., Devor D.C. (eds) Studies of Epithelial Transporters and Ion Channels. Physiology in Health and Disease. Springer, Cham. https://doi.org/10.1007/978-3-030-55454-5_6

  • Abramson J, Wright EM. Function Trumps Form in Two Sugar Symporters, LacY and vSGLT. Int J Mol Sci. 2021 Mar 30;22(7):3572. doi: 10.3390/ijms22073572. PMID: 33808202; PMCID: PMC8037263.

  • Loo D.D.F., Wright E.M. (2020) A Frog Model for CSF Secretion. In: Praetorius J., Blazer-Yost B., Damkier H. (eds) Role of the Choroid Plexus in Health and Disease. Physiology in Health and Disease. Springer, New York, NY. https://doi.org/10.1007/978-1-0716-0536-3_3

  • Wright EM. SGLT2 and cancer. Pflugers Arch. 2020 Sep;472(9):1407-1414. doi: 10.1007/s00424-020-02448-4. Epub 2020 Aug 20. PMID: 32820343; PMCID: PMC7462911.

  • Wright EM, Martín MG, Turk E. Wright E.M., & Martín M.G., & Turk E Wright, Ernest M., et al.Familial Glucose-Galactose Malabsorption and Hereditary Renal Glycosuria. In: Valle DL, Antonarakis S, Ballabio A, Beaudet AL, Mitchell GA. Valle D.L., & Antonarakis S, & Ballabio A, & Beaudet A.L., & Mitchell G.A.(Eds.),Eds. David L. Valle, et al.eds. The Online Metabolic and Molecular Bases of Inherited Disease. McGraw Hill; 2019. https://ommbid.mhmedical.com/content.aspx?bookid=2709§ionid=225555433

  • Bisignano P., Ghezzi C., Hyunil J, Polizzi N., Althoff T., Kalyanaraman C., Friemann R, Jacobson M, Wright EM, and Grabe M. (2018). Inhibitor binding mode and allosteric regulation of Na+-glucose symporters. Nature Communications. 2018 Dec 7;9(1):5245. doi: 10.1038/s41467-018-07700-1.
     
  • Ghezzi, C., Loo, D.D.F., and Wright, E.M. (2018) Physiology of renal glucose handling via SGLT1, SGLT2 and GLUT2. Diabetologia (DOI: 10.1007/s00125-018-4656-5).
     
  • Sala-Rabanal, M., Ghezzi, C.,  Hirayama, B.,  Kepe, V., Liu, J.,  Barrio, J.R., and Wright, E.M. (2018) Intestinal absorption of glucose in mice as determined by positron emission tomography. J Physiology, 596(13):2473-2489. doi: 10.1113/JP275934. Epub 2018 Jun 5.
     
  • Kepe, V., Scafoglio, C., Jie Liu, J.,  Yong, W.H. Marvin Bergsneider, Sung-Cheng Huang, S-C., Barrio, J.R.,  Wright, E.M.  (2018) Positron emission tomography of sodium glucose cotransport activity in high-grade astrocytomas. J Neuro-Oncology, doi.org/10.1007/s1106.
     
  • Paz, A., Claxton, D.P., Kumar, J.P., Kazmier, K., Bisignano, P., Sharma, S., Nolte, S.A., Liwag, T.M., Nayak, V., Wright, E.M. Grabe, M., Mchaourab, H.S., Abramson, J. (2018) Conformational transitions of the sodium-dependent sugar transporter, vSGLT. PNAS March 5, 2018. 201718451; published ahead of print March 5, 2018.
      
  • Wright, E.M., Ghezzi, C., and Loo, D.D.F., (2017) Novel and Unexpected Functions of SGLTs. Physiology. 32:435-443.
     
  • Gorraitz, E., Hirayama, BA., Paz, A., Wright, EM., Loo, DDF., (2017) Active site voltage clamp fluorometry of the sodium glucose cotransporter. Proc Natl Acad Sci U S A., Published Online 10/31/17.

Additional Papers on Pub Med